SARS-CoV N
Reactivité: SARS Coronavirus (SARS-CoV), Virus
WB, IHC (p)
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB 1:1000-1:5000 ELISA 1:5000-1:10000
Restrictions
For Research Use only
Concentration
1 mg/mL
Buffer
0.2 μm filtered solution in PBS
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Antigène
SARS-Coronavirus Nucleocapsid Protein (SARS-CoV N)
Autre désignation
SARS-CoV Nucleoprotein / NP
Sujet
Coronavirus NP,coronavirus Nucleocapsid,coronavirus Nucleoprotein,cov np,ncov NP,novel coronavirus NP,novel coronavirus Nucleocapsid,novel coronavirus Nucleoprotein,NP,Nucleocapsid,Nucleoprotein,Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.